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Facts About...


Reason for taking this medicine

Pyridoxine is a B vitamin given to people who are taking the tuberculosis (TB) medications isoniazid (INH) or pyrazinamide (PZA) as INH and PZA take pyridoxine out of the body.

How to take this medicine

  • It is important that you take vitamin B6 as prescribed
  • Do not take more vitamin B6 than you have been told to take by your doctor/health care provider
  • If you forget to take a dose of vitamin B6, take it on the same day that you missed it
  • You can take vitamin B6 with or without food
  • Do not store vitamin B6 in areas where there is direct sunlight, heat and/or moisture


  • Tell your doctor/health care provider and pharmacist about any drug allergies before starting vitamin B6
  • Always tell your doctor/health care provider and pharmacist if you are taking other medicine or vitamins
  • While most people can take vitamin B6 with no problem, in high doses (e.g., >2g per day) vitamin B6 may cause some side effects:
    • numbness, tingling or burning in hands and/or feet
    • headache
    • nausea

Check with your doctor/health care provider if you have any side effects that you are concerned about.

August 2016