Enhancing Cognitive Health in Dementia Through Co-Designed Exergaming and Digital Twins Technology

Dementia is a progressive neurological condition that affects memory, thinking, and daily functioning. Global cases are projected to triple by 2050, with Canadian cases expected to rise by nearly 187%, creating increasing pressure on health and community care. Up to 45% of dementia risk is linked to modifiable factors identified by Livingston, including physical inactivity, social isolation, depression, and cognitive inactivity. In this project, digital twins are used to model and simulate dementia progression, longitudinal patterns, and potential treatment responses by integrating multimodal data (e.g., biomarkers, imaging, cognitive assessments, and behavioural patterns) within a web-based platform, supporting the development of adaptive interventions that strengthen cognitive stimulation, physical activity, social engagement, and overall well-being for PLwD and their caregivers.

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